For the modding community, v1.7.9B is the new baseline. Because Nicalis announced that future updates would be sparse (focusing on security and critical crashes only), modders treat v1.7.9B as the "definitive" Isaac API. The famous community expansion mod (which adds new enemies, items, and a "Mega Satan 2.0" fight) explicitly requires v1.7.9B to run. If you try to run modern mods on v1.7.6, the Lua scripts will fail.
: This exact version is frequently cited in the community because it is the baseline required to run REPENTOGON , a popular C++ script extender mod that massively improves the game's Lua API and performance. The Binding of Isaac- Repentance -v1.7.9B-