This is the most modern cause. Windows 10 and 11 have a feature called Core Isolation (part of Windows Security) that uses virtualization to protect the core kernel.
I've conducted a thorough search and found a few resources that might help you understand and resolve the Kaspersky error 27300 related to klif.sys-x64. Here's a compiled paper: kaspersky error 27300 klif.sys-x64
Before attempting a fresh install, ensure all traces of previous versions are gone. This is the most modern cause
Warning: Disabling Windows Defender drivers may require temporarily turning off “Memory Integrity” (Core Isolation) in Windows Security. kaspersky error 27300 klif.sys-x64